Picture 44

This picture shows Cryptococcus neoformans in Muscicarmine stain.

Cryptococcus neoformans

Morphology: A yeast that is encapsulated with a polysaccharide capsule and reproduces asexually by budding

Route of transmission: Inhalation of spores and via skin lesions

Investigations: Lumbar puncture, Indian ink stain, Muscicarmine stain for the capsule

Diseases:

Meningoencephalitis

Pulmonary cryptococcosis

Skin and bone lesions in disseminated cases

Treatment:

Begin with IV amphotericin B and flucytosine, then change to fluconazole

 

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