Picture 23

This picture shows Shigella dysenteriae (the yellowish bacterial growth on the left) and Klebsiella pneumoniae (the pinkish bacterial growth on the right) cultured in MacConkey's agar.

Shigella dysenteriae

Morphology: Gram negative cocci that do not ferment lactose, do not produce spores and is motile

Route of transmission: Food, fingers, flies, faeces

Investigations: Gram stain, organism cultured on MacConkey's agar and Triple Sugar Iron (TSI) medium

Diseases:

Usually mild watery diarrhea in developed countries and severe "bacillary dysentery" in developing countries

Treatment:

No antibiotics are given in mild cases

In severe cases, ciprofloxacin or trimethoprim-sulfamethoxazole is prescribed

 

Klebsiella pneumoniae

Morphology: Gram negative cocci that ferment lactose, has a very large capsule which gives it a mucoid appearance

Route of transmission: Fomites, aerosol

Investigations: Gram stain, organism cultured on MacConkey's agar

Diseases:

Lower respiratory tract infections (likely to progress to empyema and lung abscess)

Urinary tract infections

Surgical wound infections

Treatment:

Due to varied antibiotic resistance, gentamicin and cefotaxime are used empirically until results of sensitivity tests are known. Usually treatment consists of an aminoglycoside and a cephalosporin to produce synergistic effects.

 

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