FRONTIERS IN BIOSCIENCE, VOLUME 4, 1999
TABLE OF CONTENTS



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RESEARCH ARTICLES: BASIC SCIENCE

A new CD44v3-containing isoform is involved in tumor cell growth and migration during human breast carcinoma progression
Eric D. Kalish, M.D., Naoko Iida, Frederick L. Moffat, and Lilly Y.W. Bourguignon

[Frontiers in Bioscience 4, a1-8, January 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9872731]

The Alzheimer's plaques, tangles and memory deficits may have a common origin. part V: why is Ca2+ signal lower in the disease?
Ming Chen and Hugo L. Fernandez

[Frontiers in Bioscience 4, a9-15, April 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10099137]

The Alzheimer's plaques, tangles and memory deficits may have a common origin. part V: why is Ca2+ signal lower in the disease?
Ming Chen and Hugo L. Fernandez

[Frontiers in Bioscience 4, a9-15, April 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10099137]

RESEARCH ARTICLES: CLINICAL SCIENCE

Transcutaneous electrohepatogram in humans
Ahmed Shafik

[Frontiers in Bioscience 4, b1-4, February 15 ,1999]
[Abstract] [Full text] [PDF] [PubMed#:9989952]

Study of the electric activity of the cirrhotic liver with identification of an electrohepatogram
Ahmed Shafik

[Frontiers in Bioscience 4, b5-8, May 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10331994]

TECHNICAL NOTES AND PROTOCOLS

REVIEWS: BASIC SCIENCE

Aminoglycoside resistance mediated by the bifunctional enzyme 6'-N-aminoglycoside acetyltransferase-2"-O-aminoglycoside phosphotransferase
Esther Culebras, and José L. Martínez

[Frontiers in Bioscience 4, d1-8, January 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9872730]

Aminoglycoside phosphotransferases: proteins, structure, and mechanism
Gerard D. Wright and Paul R. Thompson

[Frontiers in Bioscience 4, d9-21, January 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9872733]

Protein dephosphorylation and the intracellular control of the cell number
Norbert Berndt

[Frontiers in Bioscience, 4 d22-42, January 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9872729]

Bacterial plasmids: replication of extrachromosomal genetic elements encoding resistance to antimicrobial compounds
Luis A. Actis, Marcelo E. Tolmasky and Jorge H. Crosa

[Frontiers in Bioscience 3, d43-62, January 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9872728]

Developing a snapshot of the ATP binding domain(s) of aminoglycoside phosphotransferases
Michael H. Perlin , Scott A. Brown, and Jaydev N. Dholakia

[Frontiers in Bioscience, 4 d63-71, January 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9872732]

Regulation of platelet-derived growth factor signaling by activated p21Ras
Ligaya L. Stice, Cyrus Vaziri and Douglas V. Faller

[Frontiers in Bioscience 4, d72-86, January 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9889183]

Ontogeny of EGF receptors in the human gut
Pierre Chailler and Daniel Ménard

[Frontiers in Bioscience 4, d87-101, January 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9889180]

Focal adhesion kinase in integrin-mediated signaling
Leslie A. Cary and Jun-Lin Guan

[Frontiers in Bioscience 4, d102-113, January 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9889179]

Sperm disintegrins, egg integrins, and other cell adhesion molecules of mammalian gamete plasma membrane interactions
Janice P. Evans

[Frontiers in Bioscience 4, d114-131, January 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9889181]

The chromosomal 2'-N-acetyltransferase of providencia stuartii: physiological functions and genetic regulation
David R. Macinga and Philip N. Rather

[Frontiers in Bioscience 4, d132-140, February 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9924143]

Signal relays in the VEGF system
Nathalie Ortéga, Helen Hutchings, Jean Plouët

[Frontiers in Bioscience 4, d141-152, February 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9924144]

Polyomaviruses and human tumors: a brief review of current concepts and interpretations
John A. Lednicky and Janet S. Butel

[Frontiers in Bioscience 4, d153-164, February 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9989950]

Signal transduction by fibroblast growth factor receptors
Peter Klint and Lena Claesson-Welsh

[Frontiers in Bioscience 4, d165-177, February 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9989949]

Biological significance of the expression of urokinase-type plasminogen activator receptors (uPARs) in brain tumors
Sanjeeva Mohanam, Candece L. Gladson, Chilukuri N. Rao1 and Jasti S. Rao

[Frontiers in Bioscience 4, d178-187, February 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9989951]

The role of integrins in the malignant phenotype of gliomas
Joon H. Uhm, Candece L. Gladson, & Jasti S. Rao

[Frontiers in Bioscience 4, d188-199, February 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9989953]

Latency of varicella zoster virus; a persistently perplexing state
Paul R. Kinchington

[Frontiers in Bioscience 4, d200-211, February 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9989948]

Comparison of ZP3 protein sequences among vertebrate species: to obtain a consensus sequence for immunocontraception
Xiaolong Zhu and Rajesh K. Naz

[Frontiers in Bioscience 4, d212-215, March 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10051457]

T cells and aging (update February 1999)
Graham Pawelec , Rita B. Effros, Calogero Caruso, Ed Remarque, Yvonne Barnett, Rafael Solana

[Frontiers in Bioscience 4, d216-269, March 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10051456]

Phosphorylase phosphatase: new horizons for an old enzyme
Ernest Y.C. Lee, Lifang Zhang, Sumin Zhao, Qun Wei, Jun Zhang, Zhi Qing Qi and Esther R. Belmonte

[Frontiers in Bioscience 4, d270-285, March 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10077543]

Lineage commitment and maturation of epithelial cells in the gut
Sherif M. Karam

[Frontiers in Bioscience 4, d286-298, March 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10077541]

Nutritional regulation of gastrointestinal growth
David M. Klurfeld

[Frontiers in Bioscience 4, d299-302, March 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10079094]

Gastrointestinal mucosal regeneration: role of growth factors
M. K. Jones, M. Tomikawa, B. Mohajer and A. S. Tarnawski

[Frontiers in Bioscience 4, d303-309, March 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10077540]

Integrins and human intestinal cell functions
Jean-François Beaulieu

[Frontiers in Bioscience 4, d310-321, March 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10077538]

Aging and cancer of the stomach and colon
Richard Jaszewski, Murray N. Ehrinpreis and Adhip P.N. Majumdar

[Frontiers in Bioscience 4, d322-328, March 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10077539]

Polyps as biomarkers for colorectal neoplasia
M. Tobi

[Frontiers in Bioscience 4, d329-338, March 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10077546]

Antioxidant enzymes and their implications in pathophysiologic processes
José M. Matés and Francisca Sánchez-Jiménez

[Frontiers in Bioscience 4, d339-345, March 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10077544]

Epstein-barr virus immortalization and latency
David T. Rowe

[Frontiers in Bioscience 4, d346-371, March 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10077545]

Life among the primitives: protein O-phosphatases in prokaryotes
Peter J. Kennelly and Malcolm Potts

[Frontiers in Bioscience 4, d372-385, March 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10077542]

Gene therapy approaches to HIV-infection : immunological strategies : use of T bodies and universal receptors to redirect cytolytic T-cells
Natacha Bitton, Guy Gorochov, Patrice Debre And Zelig Eshhar

[Frontiers in Bioscience 4, d386-393, April 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10099136]

Molecular surface sequence analysis of several E. coli enzymes and implications for existence of casein kinase-2 bacterial predecessor
Ivan Torshin

[Frontiers in Bioscience 4, d394-407, April 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10099138]

Comparison of calcium import as a function of contraction in the aortic smooth muscle of Sprague-Dawley, Wistar Kyoto and spontaneously hypertensive rats
Munir A. Rahmani, Gerald DeGray, Valentina David, Franklin R. Ampy and Leslie Jones

[Frontiers in Biosciece 4, d408-415, April 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10209059]

Xenotransplantation - state of the art - Update 1999
L. Bühler, T. Friedman, J. Iacomini, and D.K.C. Cooper

[Frontiers in Biosciece 4, d416-432, April 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10209058]

Conjugative transfer in the dissemination of beta-lactam and aminoglycoside resistance
Virginia L. Waters

[Frontiers in Bioscience 4, d433-456, May 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10228095]

Human immunodeficiency virus and the hematopoietic repertoire: implications for gene therapy
Nicki Panoskaltsis, and Camille N. Abboud

[Frontiers in Bioscience 4, d457-467, May 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10228094]

Gene therapy for the treatment of AIDS: animal models and human clinical experience
Rafael G. Amado , Ronald T. Mitsuyasu1 and Jerome A. Zack

[Frontiers in Bioscience, 4, d468-475, May 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10331991]

Direct and indirect antigen recognition: the pathways to allograft immune rejection
Gilles Benichou

[Frontiers in Bioscience 4, d476-480, May 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10331992]

Lentiviral vectors and gene therapy
Ekaterina Klimatcheva, Joseph D. Rosenblatt and Vicente Planelles

[Frontiers in Bioscience 4, d481-496, June 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:Pending]

Ribozymes in gene therapy of HIV-1
Janet L. Macpherson, Julie A. Ely, Lun-Quan Sun, and Geoff P. Symonds

[Frontiers in Bioscience 4, d497-505, June 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:Pending]

Aldehyde-protein adducts in the liver as a result of ethanol-induced oxidative stress
Onni Niemelä

[Frontiers in Bioscience 4, d506-513, June 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:Pending]

Oxidant anti-oxidant imbalance and effects of ethanol
Catherine Rivier

Frontiers in Bioscience 4, d514-519, June 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:Pending]

REVIEWS: CLINICAL SCIENCE

Y chromosome and male infertility
Csilla Krausz and Ken McElreavey

[Frontiers in Bioscience 4, e1-8, January 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9889182]

Naturally-occurring antisperm antibodies in men: interference with fertility and implications for treatment
Felice Francavilla, Rossella Romano, Riccardo Santucci, Grazia La Verghetta, Piera D’Abrizio and Sandro Francavilla

[Frontiers in Bioscience 4, e9-25, February 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:9924142]

Stem cell directed gene therapy
Barbara C. Engel and Donald B. Kohn

[Frontiers in Bioscience 4, e26-33, May 1, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10228093]

Inhibitor resistant class A beta-lactamases
Robert A. Bonomo and Louis B. Rice

[Frontiers in Bioscience 4, e34-41, May 15, 1999]
[Abstract] [Full text] [PDF] [PubMed#:10331993]